GIVE

Dr. Dean W. Gabriel

Professor


Dean Gabriel bio picture

Contact

Room #2559 Fifield Hall, 2550 Hull Rd.
Gainesville, FL, 32611
(352) 392-7239
dgabr@ufl.edu

Background
  • Ph.D. Michigan State University, 1981
  • M.S. Michigan State University, 1976
  • B.A. Michigan State University, 1974
  • B.S. University of Wisconsin, 1964

Contact

Room #2559 Fifield Hall, 2550 Hull Rd.
Gainesville, FL, 32611
(352) 392-7239
dgabr@ufl.edu

Background
  • Ph.D. Michigan State University, 1981
  • M.S. Michigan State University, 1976
  • B.A. Michigan State University, 1974
  • B.S. University of Wisconsin, 1964
Research

About

Research in my lab is in the areas of genetics, physiology and molecular biology of plant/microbe interactions. We are currently working on the structure, function and expression of cloned pathogen virulence genes, especially those involving citrus canker disease, cotton blight and common bean blight. Citrus canker disease is a quarantined pathogen in the U.S. and must be kept under BL-3 physical containment. We are working on methods to block pathogen signal molecules transferred to the plant nucleus. We have research projects to engineer resistance to bacterial pathogens and insect pests. Other projects involve research on the population structure, epidemiology, taxonomy, and detection of Xanthomonas. Graduate students in my lab have the option of majoring in either Plant Pathology or Plant Molecular and Cell Biology. I teach on the subjects of microbial genetics, population genetics, host/parasite interactions, and resistance gene management in two formal courses: "PLP6502, Genetics of Plant/Microbe Interactions" and "PCB5065, Advanced Genetics."

Publications
  • Jain, M., Fleites, L. A., and Gabriel, D. W. 2015 Prophage encoded peroxidase in'Candidatus Liberibacter asiaticus' is a secreted effector that suppresses plant defenses. Mol. Plant Microbe Interact. DOI: 10.1094/MPMI-07-15-0145-R.
  • Zhang S, Chakrabarty PK, Fleites LA, Rayside PA, Hopkins DL, Gabriel DW. 2015 Three New Pierce's Disease Pathogenicity Effectors Identified Using Xylella fastidiosa Biocontrol Strain EB92-1. PLoS One 10:e0133796. doi: 10.1371/journal.pone.0133796.
  • Fleites LA, Jain M, Zhang S, Gabriel DW 2014 Candidatus Liberibacter asiaticus prophage late genes may limit host range and culturability. Appl Environ Microbiol. 80:6023-30.
  • Wulff, NA, Zhang, S, Setubal, JC, Almeida, NF, Martins EC, Harakava, R, Kumar, D, Rangel, LT, Foissac, X, Bove, J, Gabriel, DW. 2014 The complete genome sequence of Candidatus Liberibacter americanus, associated with citrus Huanglongbing. Mol Plant Microbe Interact. 27:163-176. Epub ahead of print] PMID: 24200077.
  • Fleites, L, Mensi, I, Gargani, D, Zhang, S, Rott, PC, Gabriel, DW. 2013 Xanthomonas albilineans OmpA1 appears to be functionally modular and both the OMC and C-like domains are necessary for leaf scald disease of sugarcane. Molec. Plant Microbe Interact. Jun 12. [Epub ahead of print] PMID: 23758144.
  • Rott, P, Fleites, LA, Mensi, I, Sheppard, L, Daugrois, JH, Dow, JM, Gabriel, DW. 2013 The RpfCG two-component system negatively regulates the colonization of sugar cane stalks by Xanthomonas albilineans. Microbiology 159:1149-59. doi: 10.1099/mic.0.065748-0.
  • Hoffman MT, Doud MS, Williams L, Zhang MQ, Ding F, Stover E, Hall D, Zhang S, Jones L, Gooch M, Fleites L, Dixon W, Gabriel D, Duan YP. 2013 Heat treatment eliminates 'Candidatus Liberibacter asiaticus' from infected citrus trees under controlled conditions. Phytopathology 103:15-21.
  • Pieretti I, Royer M, Barbe V, Carrere S, Koebnik R, Couloux A, Darrasse A, Gouzy J, Jacques MA, Lauber E, Manceau C, Mangenot S, Poussier S, Segurens B, Szurek B, Verdier V, Arlat M, Gabriel DW, Rott P, Cociancich S. 2012 Genomic insights into strategies used by Xanthomonas albilineans with its reduced artillery to spread within sugarcane xylem vessels. BMC Genomics 13:658. doi: 10.1186/1471-2164-13-658.
  • Zhang, S., Z. Flores-Cruz, D. Kumar, P. Chakrabarty, D. L. Hopkins, and D. W. Gabriel. 2011 The Xylella fastidiosa Biocontrol Strain EB92-1 Genome Is Very Similar and Syntenic to Pierce's Disease Strains. Journal of Bacteriology 193:5576-5577.
  • Zhang, S., Flores-Cruz, Z., Zhou, L., Kang, B. H., Fleites, L., Gooch, M. D., Wulff, N. A., Davis, M. J., Duan, Y., and Gabriel, D.W. 2011 Ca. Liberibacter asiaticus carries an excision plasmid prophage and a chromosomally integrated prophage that becomes lytic in plant infections. Molec. Plant-Microbe Interactions 24:458-468
  • Rott, P., M. Marguerettaz, L. Fleites, S. Cociancich, J. C. Girard, I. Pieretti, D. W. Gabriel, and M. Royer. 2011 Unravelling pathogenicity of Xanthomonas albilineans, the causal agent of sugarcane leaf scald. Int. Sugar J. 113:490-496.
  • Rott, P.C., Fleites, L., Marlow, G., Royer, M., and Gabriel, D.W. 2011 Identification of New Candidate Pathogenicity Factors in the Xylem-Invading Pathogen Xanthomonas albilineans by Transposon Mutagenesis. Molec. Plant-Microbe Interact. 24:594-605

About

Research in my lab is in the areas of genetics, physiology and molecular biology of plant/microbe interactions. We are currently working on the structure, function and expression of cloned pathogen virulence genes, especially those involving citrus canker disease, cotton blight and common bean blight. Citrus canker disease is a quarantined pathogen in the U.S. and must be kept under BL-3 physical containment. We are working on methods to block pathogen signal molecules transferred to the plant nucleus. We have research projects to engineer resistance to bacterial pathogens and insect pests. Other projects involve research on the population structure, epidemiology, taxonomy, and detection of Xanthomonas. Graduate students in my lab have the option of majoring in either Plant Pathology or Plant Molecular and Cell Biology. I teach on the subjects of microbial genetics, population genetics, host/parasite interactions, and resistance gene management in two formal courses: "PLP6502, Genetics of Plant/Microbe Interactions" and "PCB5065, Advanced Genetics."

Publications

AuthorsYearDescriptionPublication
Jain, M., Fleites, L. A., and Gabriel, D. W. 2015 Prophage encoded peroxidase in'Candidatus Liberibacter asiaticus' is a secreted effector that suppresses plant defenses. Mol. Plant Microbe Interact. DOI: 10.1094/MPMI-07-15-0145-R.
Zhang S, Chakrabarty PK, Fleites LA, Rayside PA, Hopkins DL, Gabriel DW. 2015 Three New Pierce's Disease Pathogenicity Effectors Identified Using Xylella fastidiosa Biocontrol Strain EB92-1. PLoS One 10:e0133796. doi: 10.1371/journal.pone.0133796.
Fleites LA, Jain M, Zhang S, Gabriel DW 2014 Candidatus Liberibacter asiaticus prophage late genes may limit host range and culturability. Appl Environ Microbiol. 80:6023-30.
Wulff, NA, Zhang, S, Setubal, JC, Almeida, NF, Martins EC, Harakava, R, Kumar, D, Rangel, LT, Foissac, X, Bove, J, Gabriel, DW. 2014 The complete genome sequence of Candidatus Liberibacter americanus, associated with citrus Huanglongbing. Mol Plant Microbe Interact. 27:163-176. Epub ahead of print] PMID: 24200077.
Fleites, L, Mensi, I, Gargani, D, Zhang, S, Rott, PC, Gabriel, DW. 2013 Xanthomonas albilineans OmpA1 appears to be functionally modular and both the OMC and C-like domains are necessary for leaf scald disease of sugarcane. Molec. Plant Microbe Interact. Jun 12. [Epub ahead of print] PMID: 23758144.
Rott, P, Fleites, LA, Mensi, I, Sheppard, L, Daugrois, JH, Dow, JM, Gabriel, DW. 2013 The RpfCG two-component system negatively regulates the colonization of sugar cane stalks by Xanthomonas albilineans. Microbiology 159:1149-59. doi: 10.1099/mic.0.065748-0.
Hoffman MT, Doud MS, Williams L, Zhang MQ, Ding F, Stover E, Hall D, Zhang S, Jones L, Gooch M, Fleites L, Dixon W, Gabriel D, Duan YP. 2013 Heat treatment eliminates 'Candidatus Liberibacter asiaticus' from infected citrus trees under controlled conditions. Phytopathology 103:15-21.
Pieretti I, Royer M, Barbe V, Carrere S, Koebnik R, Couloux A, Darrasse A, Gouzy J, Jacques MA, Lauber E, Manceau C, Mangenot S, Poussier S, Segurens B, Szurek B, Verdier V, Arlat M, Gabriel DW, Rott P, Cociancich S. 2012 Genomic insights into strategies used by Xanthomonas albilineans with its reduced artillery to spread within sugarcane xylem vessels. BMC Genomics 13:658. doi: 10.1186/1471-2164-13-658.
Zhang, S., Z. Flores-Cruz, D. Kumar, P. Chakrabarty, D. L. Hopkins, and D. W. Gabriel. 2011 The Xylella fastidiosa Biocontrol Strain EB92-1 Genome Is Very Similar and Syntenic to Pierce's Disease Strains. Journal of Bacteriology 193:5576-5577.
Zhang, S., Flores-Cruz, Z., Zhou, L., Kang, B. H., Fleites, L., Gooch, M. D., Wulff, N. A., Davis, M. J., Duan, Y., and Gabriel, D.W. 2011 Ca. Liberibacter asiaticus carries an excision plasmid prophage and a chromosomally integrated prophage that becomes lytic in plant infections. Molec. Plant-Microbe Interactions 24:458-468
Rott, P., M. Marguerettaz, L. Fleites, S. Cociancich, J. C. Girard, I. Pieretti, D. W. Gabriel, and M. Royer. 2011 Unravelling pathogenicity of Xanthomonas albilineans, the causal agent of sugarcane leaf scald. Int. Sugar J. 113:490-496.
Rott, P.C., Fleites, L., Marlow, G., Royer, M., and Gabriel, D.W. 2011 Identification of New Candidate Pathogenicity Factors in the Xylem-Invading Pathogen Xanthomonas albilineans by Transposon Mutagenesis. Molec. Plant-Microbe Interact. 24:594-605