GIVE

Dr. Rosemary Loria

Department Chair / Professor


head shot of Rosemary Loria for faculty page

Contact

Rm. # 1453 Fifield Hall, 2550 Hull Road
Gainesville, FL, 32611
(352) 273-4634
rloria@ufl.edu

Background
  • B.S., Michigan State University, 1974
  • M.S., Michigan State University, 1977
  • Ph.D., Michigan State University, 1980

Interests and Expertise

Evolution and molecular mechanisms of plant pathogenesis in Streptomyces spp. Genomics of plant pathogenic actinobacteria. Biosynthesis and regulation of the cellulose biosynthesis inhibitor, thaxtomin. Identification of secreted proteins in the virulence of streptomycetes. Secondary metabolite production and regulation in plant pathogenic Streptomyces. The role of horizontal gene transfer in the emergence of plant pathogenic bacteria.


Lab Members

Publications

AuthorsYearDescriptionPublication
Barry, S.M., J.A. Kers, E.G. Johnson, L. Song, P.R. Aston, B. Patel, S.B. Krasnoff, B.R. Crane, D.M. Gibson, R. Loria, and G.L. Challis. 2012 Cytochrome P450-catalyzed L-tryptophan nitration in thaxtomin phytotoxin biosynthesis. Nature Chem. Biol. 8: 814–816.
Huguet-Tapia, J. C., R. Loria. 2012 Draft genome sequence of Streptomyces acidiscabies 84-104, an emergent plant pathogen. J. Bacteriol. 194( 7): 1847.
Fyans J.K., Bignell D., Loria R., Toth I., Palmer T. 2012 The ESX/type VII secretion system modulates development, but not virulence, of the plant pathogen Streptomyces scabies . Mol Plant Pathol. 2012 Sep 26. doi: 10.1111/j.1364-3703.2012.00835.x.
Guan D., Grau B.L., Clark C.A. Taylor C.M., Loria R., Pettis G.S. 2012 Evidence that thaxtomin C is a pathogenicity determinant ofStreptomyces ipomoeae, the causative agent of streptomyces soil rot disease of sweet potato. Mol Plant Microbe Interact; 2012 Mar;25(3):393-401
Huguet-Tapia, J. C., J. H. Badger, R. Loria, and G. S. Pettis. 2011 Streptomyces turgidiscabies Car8 contains a modular pathogenicity island that shares virulence genes with other actinobacterial plant pathogens. Plasmid, 65: 118-124.
Seipke, R.F., L. Song, J. Bicz, P. Laskaris, A. M. Yaxley, G. L. Challis, and R. Loria.  2011 The plant pathogen Streptomyces scabies 87-22 has a functional pyochelin biosynthetic pathway that is regulated by TetR- and AfsR-family proteins. Microbiology 157:2681-2693.
Bignell, R. D., R. F. Seipke, J.C. Huguet-Tapia, A. H. Chambers, R. J. Parry and R. Loria.. 2010 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions. Mol Plant Microbe Interact, 23:161-175.
Bignell, R. D., J.C. Huguet-Tapia, M. V. Joshi, G. S. Pettis and R. Loria. 2010 What does it take to be a pathogen: genomic insights from Streptomyces species. Antonie Van Leeuwenhoek, 98:179-94.
Joshi, M., S. Mann, H. Antelmann, D. Widdick, J. Fyans, G. Chandra, M. Hutchings, I. Toth, M. Hecker, R. Loria and T. Palmer. 2010 The Tat pathway exports multiple virulence proteins in the plant pathogen Streptomyces scabies Mol Microbiol, 77:252-271.
Johnson, E. G., S. B. Krasnoff, D. R. D. Bignell, W.-C. Chung, T. Tao, R. J. Parry, R. Loria and D. M. Gibson. 2009 4-Nitrotryptophan is a substrate for the non-ribosomal peptide synthetase TxtB in the thaxtomin A biosynthetic pathway. Mol Plant Microbe Interact, 73:409–418.

Contact

Rm. # 1453 Fifield Hall, 2550 Hull Road
Gainesville, FL, 32611
(352) 273-4634
rloria@ufl.edu

Background
  • B.S., Michigan State University, 1974
  • M.S., Michigan State University, 1977
  • Ph.D., Michigan State University, 1980
About

Interests and Expertise

Evolution and molecular mechanisms of plant pathogenesis in Streptomyces spp. Genomics of plant pathogenic actinobacteria. Biosynthesis and regulation of the cellulose biosynthesis inhibitor, thaxtomin. Identification of secreted proteins in the virulence of streptomycetes. Secondary metabolite production and regulation in plant pathogenic Streptomyces. The role of horizontal gene transfer in the emergence of plant pathogenic bacteria.


Lab Members

Publications
  • Barry, S.M., J.A. Kers, E.G. Johnson, L. Song, P.R. Aston, B. Patel, S.B. Krasnoff, B.R. Crane, D.M. Gibson, R. Loria, and G.L. Challis. 2012. Cytochrome P450-catalyzed L-tryptophan nitration in thaxtomin phytotoxin biosynthesis. Nature Chem. Biol. 8: 814–816.
  • Huguet-Tapia, J. C., R. Loria. 2012. Draft genome sequence of Streptomyces acidiscabies 84-104, an emergent plant pathogen. J. Bacteriol. 194( 7): 1847.
  • Fyans J.K., Bignell D., Loria R., Toth I., Palmer T. 2012. The ESX/type VII secretion system modulates development, but not virulence, of the plant pathogen Streptomyces scabies. Mol Plant Pathol. 2012 Sep 26. doi: 10.1111/j.1364-3703.2012.00835.x.
  • Guan D., Grau B.L., Clark C.A. Taylor C.M., Loria R., Pettis G.S. 2012. Evidence that thaxtomin C is a pathogenicity determinant ofStreptomyces ipomoeae, the causative agent of streptomyces soil rot disease of sweet potato. Mol Plant Microbe Interact; 2012 Mar;25(3):393-401
  • Huguet-Tapia, J. C., J. H. Badger, R. Loria, and G. S. Pettis.  2011.  Streptomyces turgidiscabies Car8 contains a modular pathogenicity island that shares virulence genes with other actinobacterial plant pathogens.  Plasmid, 65: 118-124.
  • Seipke, R.F., L. Song, J. Bicz, P. Laskaris, A. M. Yaxley, G. L. Challis, and R. Loria. 2011. The plant pathogen Streptomyces scabies 87-22 has a functional pyochelin biosynthetic pathway that is regulated by TetR- and AfsR-family proteins. Microbiology 157:2681-2693.
  • Bignell, R. D., R. F. Seipke, J.C. Huguet-Tapia, A. H. Chambers, R. J. Parry and R. Loria..  2010. Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions. Mol Plant Microbe Interact, 23:161-175.
  • Bignell, R. D., J.C. Huguet-Tapia, M. V. Joshi, G. S. Pettis and R. Loria.  2010.  What does it take to be a pathogen: genomic insights from Streptomyces species.  Antonie Van Leeuwenhoek, 98:179-94.
  • Joshi, M., S. Mann, H. Antelmann, D. Widdick, J. Fyans, G. Chandra, M. Hutchings, I. Toth, M. Hecker, R. Loria and T. Palmer. 2010. The Tat pathway exports multiple virulence proteins in the plant pathogen Streptomyces scabies. Mol Microbiol, 77:252-271.
  • Johnson, E. G., S. B. Krasnoff, D. R. D. Bignell, W.-C. Chung, T. Tao, R. J. Parry, R. Loria and D. M. Gibson. 2009. 4-Nitrotryptophan is a substrate for the non-ribosomal peptide synthetase TxtB in the thaxtomin A biosynthetic pathway. Mol Plant Microbe Interact, 73:409–418.