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Wen-Yuan Song

Assistant Professor

picture of Wen-Yuan Song for faculty bio page


Phone: (352) 273-4652
Office: Rm. #2431, Fifield Hall
2550 Hull Road
Gainesville, FL, 32611




Dr. Song's lab is interested in the mechanisms by which the rice Xa21 gene confers resistance against the bacterial blight disease and the approaches to engineering broad spectrum and durable resistance in crops.

  • Education

    Ph.D. Plant Molecular Biology, Institute of Genetics, Academia Sinica, China, 1995

    B.S. Biochemistry, Lanzhou University, China, 1988

  • Research

    Research in my laboratory is focused on molecular mechanisms of the plant immune system. We are particularly interested in the roles of protein kinases, E3 ubiquitin ligases and transcription factors in plant immunity. Our models include bacterial blight disease of rice caused by Xanthmonas oryzae pv. oryzae, citrus canker disease caused by Xanthomonas citri subsp. citri and citrus greening. Our goal is to better utilize the plant immune system for disease control in crops.

  • Teaching

    Courses Taught

    • PLP 6303 Host-Parasite Interactions II
    • PLP 6921 Plant Pathology Colloquium
    • PLP6932  Plant Pathology Seminar


Ding X, Richter T, Chen M, Fujii H, Xie M, Zheng X, Kanrar S, Stevenson RA, Dardick C, Li Y, Jiang H, Zhang Y, Yu F, Zhu L, Farmerie WG, Gribskov M, Zhu JK, Fromm ME, Ronald PC, and Song WY. 2009 A rice kinase-protein interaction map. Plant Physiology 149: 1478-1492.
Wang Y, Pi LY, Chen X, Chakrabarty PK, Jiang J, Lopez De Leon A, Liu G, Li L, Benny U, Oard J, Ronald PC, and Song WY. 2006 The Ubiquitin Ligase XB3 interacts with the rice receptor-like kinase XA21 and is required for XA21-mediated disease resistance. Plant Cell 18: 1-12.
Ding, X., Zhang, Y., Song, W.-Y. 2006 Use of rolling circle amplification for large-scale yeast two-hybrid analyses.  In Plant-Pathogen Interactions of Methods in Molecular Biology; Humana Press, USA (354: 85-98).
Xu, W.-H., Wang, Y., Liu, G., Chen, X., Tinjuangjun, P., Pi, L.-Y., Zhang, Y., Song, W.-Y. 2006 The autophosphorylated Ser686, Thr688 and Ser689 residues within a putative protease cleavage motif in the juxtamembrane domain of XA21 stabilizes the rice receptor-like kinase. The Plant Journal 45: 740-751.
Nodzon, L.A., Xu, W.-H., Wang, Y., Pi, L.-Y., Chakrabarty, P.K., Song, W.-Y. 2004 The ubiquitin ligase Xbat-32 regulates lateral root development in Arabidopsis. The Plant Journal 40: 996-1006.
Ding, X., Cory, G., Song, W.-Y. 2004 . A high-throughput system to verify candidate interactors from yeast two-hybrid screening using rolling circle amplification. Analytical Biochemistry 331: 195-197.
Ding, X., Snyder, A.K., Shaw, R., Farmerie, W.G., Song, W.-Y. 2003 . Direct retransformation of yeast with plasmid DNA isolated from single yeast colonies using rolling circle amplification. Biotechniques 35: 774-779.
Liu, G., Pi, L.-Y., Walker, J.C., Ronald, P.C., Song, W.-Y. 2002 Biochemical characterization of the kinase domain of the rice disease resistance receptor-like kinase XA21. Journal of Biological Chemistry 277: 20264-20269.
Song, W.-Y., Pi, L.-Y., Wang, G.-L., Gardner, J., Holsten, T.E., and Ronald, P.C. 1997 Evolution of the rice Xa21 disease resistance gene family. Plant Cell 9: 1279-1287.
Song, W.-Y., Wang, G.-L., Chen, L.-L., Kim, H.-S., Pi, L.-Y., Holsten, T.E., Gardner, J., Wang, B., Zhai, W.-X., Zhu, L.-H., Fauquet, C., and Ronald, P.C. 1995 A receptor kinase-like protein encoded by the rice disease resistance gene, Xa21. Science 270: 1804-1806.